SPATIAL DYNAMICS OF CD39+CD8+ EXHAUSTED T CELL REVEAL TERTIARY LYMPHOID STRUCTURES-MEDIATED RESPONSE TO PD-1 BLOCKADE IN ESOPHAGEAL CANCER

Spatial dynamics of CD39+CD8+ exhausted T cell reveal tertiary lymphoid structures-mediated response to PD-1 blockade in esophageal cancer

Abstract Despite the success of immune checkpoint blockade (ICB) therapy for esophageal squamous cell cancer, the key immune cell populations that affect ICB efficacy remain unclear.Here, imaging mass cytometry of tumor tissues from ICB-treated patients identifies a distinct cell population of CD39+PD-1+CD8+ T cells, LADIES SHOES FLAT specifically

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Cartographic depiction of religious buildings and cemeteries on cadastral maps created during the first cadastral survey of Bosnia and Herzegovina

This paper deals with cartographic depictions of religious Collections facilities and cemeteries in Bosnia and Herzegovina on cadastral maps created during the Austro-Hungarian administration.It shows how cartographic depictions of these plans changed over time, based on collections of topographic symbols published in the late 19th and the early 20

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Against Social Kind Anti-Realism

The view that social kinds (e.g., money, migrant, marriage) are mind-dependent is a prominent one in the social ontology literature.However, in addition to Diabetes Monitoring - Glucose Meter Controls the claim that social kinds are mind-dependent, it is often asserted that social kinds are not real because they are mind-dependent.Call this view so

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